Drosophila Cdi4 is a p21/p27/p57-like cyclin-dependent kinase inhibitor with specificity for cyclin E complexes
نویسندگان
چکیده
While we were characterizing Cdi4 and its interaction with cyclin E, two groups, one led by de Nooij and Hariharan and the other by Lane and Lehner, independently isolated mutations in a gene, decapo, that encodes Cdi4. Both groups presented elegant experiments demonstrating the importance of decapo in regulating the cell cycle during development (de Nooij et al., 1996. Cell 87, 1237-1247 [Medline]; Lane et al., 1997. Cell 87, 1225-1235 [Medline]). Our paper includes some data not duplicated by the work from de Nooij et al., or Lane et al., including in vitro kinase inhibition assays, yeast interaction assays, and our sequence analyses. This paper is not published. To reference data in this paper please refer to R.L. Finley, B. Cohen, an R. Brent, personal communication, or refer to this web site.
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